On the Asset Responsibility Centers list you can create a connection between maintenance responsibility center and (standard) responsibility center.
Thanks to this connection - when the Purchase Order is created for the work order and the work order has an asset responsibility connected with a responsibility center - a standard responsibility center is assigned to the created Purchase Order.
When there is no such connection - created PO will have the Responsibility Center defined in the User Setup table.
When you are assigning lines to already existing Purchase Order - no changes are applied to the Responsibility Center that is on the PO.
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